Heart Health: Long-Term Melatonin Use Linked to Cardiovascular Risk
New research indicates that individuals with insomnia who take melatonin supplements for over a year may face an increased risk of heart failure compared to those who do not use this common sleep aid.
The study found that long-term melatonin users were more likely to be diagnosed with heart failure, require hospitalization for the condition, or die from any cause.
Study Presentation and Status
This preliminary research will be presented at the American Heart Association’s Scientific Sessions 2025 in New Orleans. The findings have not yet undergone peer review or been published in a scientific journal.
Research Cautions and Implications
Researchers emphasized that their findings do not prove a direct cause-and-effect relationship between melatonin use and heart failure. Nevertheless, these results raise safety concerns about prolonged melatonin supplementation and suggest further studies are needed to evaluate cardiovascular risks.
Concerns About Supplement Regulation
Many melatonin supplements are available over-the-counter without prescriptions and lack regulatory oversight. This allows individuals to use them without medical supervision, which may increase potential risks.
“Melatonin supplements may not be as harmless as commonly assumed.”
Summary
This study highlights possible cardiovascular risks linked to extended melatonin use, urging caution and further research on its long-term safety.
Author's summary: Prolonged melatonin use for insomnia may raise heart failure risk, underscoring the need for regulated use and more thorough cardiovascular safety studies.